Mots-C

140,00 

15 w magazynie

Kategoria: SKU: 00285

Opis

Peptyd ktory leczy insulioopronosc na poziomie mitochondriow . Tak w skrocie zeby nie pisac w huj dlugie opisu.

Efekt uboczny

MOTS-c treatment leads to a decrease in the systemic and tissue specific levels of myostatin, which may block the weakening of muscle strength. … The enhancement of energy expenditure via increasing muscle mass and browning of WAT by MOTS-c may be essential in the protection against common diseases in elderly.

Dawkowanie w huj proste. 10mg czyli flaszka domiesniowo insulinowka 1x na tydzien .
Peptyt niestety ulega szybko zniszczeniu po reknostrukcji po 2h 50% znika po 3h 90% nie aktywne.
Duzo szybciej niz IGF1 LR3.

Dluzszy opis tu:

https://www.transformyou.com/mots-c-peptide

Ponizej dla tych ktorzy lubie teoretyczna pierdologie linki do badan:

Changhan L, Jennifer Z, Brian D, Tamer S, Alejandro M, Junxiang W, Su-Jeong K, Hemal M, Andrea L. H, Rafael de C, Pinchas C. The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance. Cell Metabolism ARTICLE| VOLUME 21, ISSUE 3, P443-454, MARCH 03, 2015.
Changhan L, Kyung Hwa Kim, Pinchas C. MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism. Free Radical Biology and Medicine Volume 100, November 2016, Pages 182-187.
Joseph Reynolds, Rochelle W. Lai, Jonathan S.T. Woodhead, James H. Joly, Cameron J. Mitchell, David Cameron-Smith, Ryan Lu, Pinchas Cohen, Nicholas A. Graham, Bérénice A. Benayoun, Troy L. Merry, Changhan Lee. MOTS-c is an Exercise-Induced Mitochondrial-Encoded Regulator of Age-Dependent Physical Decline and Muscle Homeostasis. doi: https://doi.org/10.1101/2019.12.22.886432
Su‐Jeong Kim, Brendan Miller, Hemal H. Mehta, Jialin Xiao, Junxiang Wan, Thalida E. Arpawong, Kelvin Yen, Pinchas Cohen. The mitochondrial‐derived peptide MOTS‐c is a regulator of plasma metabolites and enhances insulin sensitivity. Physiologic Reports 10 July 2019. https://doi.org/10.14814/phy2.14171
Su‐Jeong Kim, Jialin Xiao, Junxiang Wan, Pinchas Cohen, Kelvin Yen. Mitochondrially derived peptides as novel regulators of metabolism. Journal of Physiology Volume 595, Issue21 1 November 2017 Pages 6613-6621.
Manjunath R. Mitochondrial Derived Peptide MOTSc promotes hepatic fatty acid metabolism and regulation by metformin. Source: Qatar Foundation Annual Research Conference Proceedings, Qatar Foundation Annual Research Conference Proceedings Volume 2018 Issue 2, Mar 2018, Volume 2018, HBPD728 DOI: https://doi.org/10.5339/qfarc.2018.HBPD728.
B.-T. HU, W.-Z. CHEN. MOTS-c improves osteoporosis by promoting osteogenic differentiation of bone marrow mesenchymal stem cells via TGF-β/Smad pathway. European Review for Medical and Pharmacological Sciences 2018; 22: 7156-7163.
Kim sJ, Xiao J, Wan J, cohen P, Yen K. Mitochondrial- ly derived peptides as novel regulators of metabo- lism. ming W, lu g, Xin s, huanYu l, Yinghao J, XiaoYing l, chengming X, banJun R, li W, zifan l. Mitochondria related peptide MOTS-c suppresses ovariectomy-induced bone loss via AMPK activation. Bio- chem Biophys Res Commun 2016; 476: 412-419.
Shah m, Kola b, baTaVelJic a, aRneTT TR, ViolleT b, sa- Xon l, KoRboniTs m, chenu c. Amp-activated protein kinase (AMPK) activation regulates in vitro bone formation and bone mass. Bone 2010; 47: 309-319.
Kasai T, banDoW K, suzuKi h, chiba n, KaKimoTo K, ohnishi T, KaWamoTo s, nagaoKa e, maTsuguchi T. Osteoblast differentiation is functionally associated with decreased amp kinase activity. J Cell Physiol 2009; 221: 740-749.
Lee, C. et al. (2015) The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metab. 21, 443–454
Zarse, K. and Ristow, M. (2015) A mitochondrially encoded hormone ameliorates obesity and insulin resistance. Cell Metab. 21, 355–356.
Olson KA, Schell JC, Rutter J. Pyruvate and metabolic flexibility: illuminating a path toward selective cancer therapies. Trends Biochem Sci. 2016;41(3):219–230.
Speakman JR. Evolutionary perspectives on the obesity epidemic: adaptive, maladaptive, and neutral viewpoints. Annu Rev Nutr. 2013;33(1):289–317.
López-Otín C, Galluzzi L, Freije JMP, Madeo F, Kroemer G. Metabolic control of longevity. Cell. 2016;166(4):802–821.
Muoio DM. Metabolic inflexibility: when mitochondrial indecision leads to gridlock. Cell. 2014;159(6):1253–1262.

Dodatkowe informacje

Waga 0,1 kg
Dystrybutor

NEOGENICA

Opinie

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